Research Assistant (Genomics Core) (Fixed Term)
The CRUK Cambridge Institute (CI), a department of the University of Cambridge, is one of Europe's top cancer research institutes. We are situated on the Addenbrooke's Biomedical Campus and are part of both the University of Cambridge School of Clinical Medicine, and the CRUK Cambridge Centre. The Institute is home to 18 research groups which cover a spectrum of research from basic experimental and computational cancer biology through translational cancer research to clinical application. The Institute's scientific Core Facilities work in partnership with the Institute's Research Groups and are a repository for deep technological expertise and knowledge, playing a fundamental role at the heart of the Institute's research community.
The CI Genomics Core (CIGC) provides Next-Generation Sequencing (NGS) services for CRUK CI as well as the wider University and collaborative laboratories across The Cambridge Biomedical Campus. The CIGC supports translational research by providing variety of bulk DNA/RNA library preps (from multiple suppliers depending on the nucleic acid quality, all highly customized), sequencing service (MiSeq, NextSeq2000, NovaSeq6000, NovaSeqX Plus and ONT PromethION24, ONT MinION) and single cell library prep service including but not limited to 10X workflows. We support cell isolation (CellenOne) for downstream single cell genomics applications and currently are expanding spatial single cell platforms (10X Visium and 10X Xenium etc.).
You'll be joining us at an exciting time as we continue to expand our genomics service encompassing ever larger scale genomics projects, and continue to develop our utilisation and innovation of sequencing technologies, library preparation methods, and single cell techniques; providing genomic data for CRUK CI and the University of Cambridge. Genomics is our passion and generating the best quality data to translate research is our mission.
The role holder will assist in the provision of these services as well as carrying out research support directly. This will include the introduction of new methods and technologies to enhance the quality of research at the Institute. Daily duties will involve RNA / DNA sample quality control, library preparation using standard kits from different suppliers, single-cell sample receipt and processing, LIMS curation, and sequencing these samples on Illumina and ONT sequencers, data analysis of quality, and interaction with users of the services. The post-holder will be involved in pilot experiments, testing and implementing new technologies including novel library preparation for bulk DNA/RNA and single cells and genomics spatial platforms, for poor and good quality materials.
It is essential the role holder interacts exceptionally well with the Genomics Core team as well as working independently as required. They will produce project documentation including writing and editing reports, presenting data to the team and generating SOP's. The ideal applicant will have a degree in biological or biotechnological sciences and be experienced with a diversity of molecular biology techniques including PCR/qPCR, and DNA/RNA library preparation, single cell library preparation, NGS short and long read sequencing. They will be an excellent communicator and team player and bring a positive impact to the Core.
This post may require some out of hours working and travel to national seminars/meetings.
Interviews are expected to be held between 16th, 17th, and 18th of December 2024
Fixed-term: The funds for this post are available for 1 years in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
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Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter and publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.
Please quote reference SW44145 on your application and in any correspondence about this vacancy.
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